Bellafill before and after for a male patient


How does Bellafill work?

Collagen is the main structural protein in the skin and composes one-third of the protein in the human body. It gives the skin its youthful-looking elasticity and strength. Over 20 types of collagen are found within the human body, providing tissue, support, strength, and structural integrity.

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As the body ages, collagen and elastin production decreases, leading to the formation of wrinkles. Bellafill stimulates Type I and Type III collagen for long-term wrinkle correction.

beautiful middle aged woman


Hyaluronic acid fillers can dissolve within a few months. However, Bellafill injections produce long-term improvements in the skin. Bellafill is composed of tiny, polymethyl methacrylate (PMMA) microspheres, suspended in a base of smooth collagen gel.

After injection, Bellafill® immediately fills and smooths wrinkles, even in the thicker skin of men. The body then uses these microspheres to create a “scaffold” or foundation on which your own collagen can develop. Your skin’s natural-looking results feel supple and smooth for up to 5 years.

Acne Scars

Bellafill is also effective in reducing acne scars. By adding volume to them, Bellafill brings scars to the level of the skin surrounding them and keeps them in place long-term. Unlike hyaluronic acid fillers, which often dissolve within a few months, Bellafill reduces the appearance of acne scarring long-term. Because the PMMA microspheres provide a “scaffold” that supports the body’s own natural collagen production, the gel will be replaced by the body’s own collagen generated over time.

Who can use Bellafill?

To be eligible for Bellafill®, patients must be 21 or older and receive the required skin test prior to treatment. In clinical studies, Bellafill® was shown to work in both men and women with a variety of skin types. If you have a history of severe allergies, are allergic to bovine collagen, are allergic to lidocaine, have a bleeding disorder, or are prone to irregular scarring, let your doctor know prior to your treatment.

When will I see results from Bellafill?

Immediately and over time! Bellafill® replaces lost volume in the skin below the indentation, wrinkle, or fold for correction that is both instantaneous and lasting.

Does Bellafill have any side effects?

You may experience temporary swelling, redness, pain, bruising, lumps or bumps, itching, and discoloration at the treatment site, but no downtime is required after Bellafill treatment. These side effects are usually temporary, resolving within 1 to 7 days.

How long has Bellafill been in use in the United States?

Bellafill® was approved by the FDA to treat nasolabial folds in October 2006, under the trade name ArteFill®. In December 2014, Bellafill® was approved by the FDA for the correction of certain types of moderate to severe acne scars in patients over 21.


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